Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SLC13A4Solute carrier family 13 member 4. (602 aa)    
Predicted Functional Partners:
SLC26A2
Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
  
 
 0.747
PSMC3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
    
 
 0.628
OR10P1
Olfactory receptor.
      
 0.600
DEFB108B
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
    
   0.575
SLC38A8
Solute carrier family 38 member 8.
   
 
 0.531
SLC5A2
Sodium/nucleoside cotransporter; Actively transports uridine into cells by Na(+) cotransport. May play a role in reabsorption of nucleosides from glomerular filtrate by the proximal tubule in kidney, and in the regulation of cardiac contractility by adenosine.
  
  
 0.511
PSMD9
PDZ domain-containing protein.
   
  
 0.510
SLC4A5
Anion exchange protein.
   
  
 0.502
SLC22A6
Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), [...]
   
  
 0.475
TEX11
Testis expressed 11.
      
 0.459
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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