Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMER3G_PROTEIN_RECEP_F1_2 domain-containing protein. (1196 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
   0.750
AP1G2
AP-1 complex subunit gamma.
      
 0.670
TMEM54
Transmembrane protein 54.
      
 0.650
AMER2
APC membrane recruitment protein 2.
      
0.643
AMER1
APC membrane recruitment protein 1.
    
 
 0.613
ARHGAP21
Rho GTPase activating protein 21.
      
 0.547
LRRC7
PDZ domain-containing protein.
   
  
 0.537
BCO1
Beta-carotene oxygenase 1.
      
 0.535
PLCH1
Phosphoinositide phospholipase C.
   
  
 0.530
EXOSC1
S1 domain-containing protein.
      
 0.515
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (36%) [HD]