Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)    
Predicted Functional Partners:
ALDH4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.960
G1SX44_RABIT
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.947
U3KNV6_RABIT
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.914
ENSOCUP00000028294
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.914
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.902
DAO
D-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity).
  
 
 0.870
LAP3
Leucine aminopeptidase 3.
    
 0.867
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
     
 0.864
P4HA3
Prolyl 4-hydroxylase subunit alpha 3.
     
 0.864
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
     
 0.864
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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