Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LDHDLactate dehydrogenase D. (484 aa)    
Predicted Functional Partners:
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.960
HAGH
Lactamase_B domain-containing protein.
    
 0.923
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.909
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.901
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.894
AGXT
Serine--pyruvate aminotransferase.
  
 
 0.888
GPT2
Glutamic--pyruvic transaminase 2.
  
 
 0.886
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.876
ME1
Malic enzyme.
  
 
 0.872
ME2
Malic enzyme.
  
 
 0.872
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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