Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC51Coiled-coil domain containing 51. (408 aa)    
Predicted Functional Partners:
ABCB8
ATP binding cassette subfamily B member 8.
    
 0.902
ZNF541
Zinc finger protein 541.
      
 0.863
ARHGAP23
Rho GTPase activating protein 23.
      
 0.770
ILVBL
IlvB acetolactate synthase like; Belongs to the TPP enzyme family.
      
 0.767
SF3B6
Splicing factor 3b subunit 6.
      
 0.712
MRPL45
Mitochondrial ribosomal protein L45.
      
 0.702
CCDC58
Uncharacterized protein.
      
 0.682
IDH3B
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
      
 0.658
DAG1
Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]
      
 0.572
VPS36
Vacuolar protein sorting 36 homolog.
      
 0.566
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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