Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MPPED1Metallophosphoesterase domain containing 1. (325 aa)    
Predicted Functional Partners:
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.616
UPRT
Uracil phosphoribosyltransferase homolog.
    
   0.599
GTF3C1
General transcription factor IIIC subunit 1.
      
 0.587
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
   0.568
NUDT13
Nudix hydrolase 13.
      
 0.558
TBATA
Thymus, brain and testes associated.
      
 0.554
RCBTB1
RCC1 and BTB domain containing protein 1.
      
 0.535
CPNE4
Copine 4.
   
  
 0.527
C14orf39
Chromosome 14 open reading frame 39.
      
 0.519
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
    
   0.518
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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