Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBL3Ubiquitin-like protein. (117 aa)    
Predicted Functional Partners:
NEDD8
NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity).
      
 0.818
SUMO1
Small ubiquitin-related modifier.
      
 0.773
G1TG12_RABIT
Small ubiquitin-related modifier.
      
 0.768
SUMO2
Small ubiquitin-related modifier.
   
  
 0.752
G1SQP5_RABIT
Small ubiquitin-related modifier.
   
  
 0.746
G1TM59_RABIT
Small ubiquitin-related modifier.
   
  
 0.745
G1TU65_RABIT
Small ubiquitin-related modifier.
   
  
 0.745
ENSOCUP00000041916
Small ubiquitin-related modifier.
   
  
 0.745
ATG12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
      
 0.728
ISG15
ISG15 ubiquitin like modifier.
      
 0.709
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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