Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HPDL4-hydroxyphenylpyruvate dioxygenase. (371 aa)    
Predicted Functional Partners:
HGD
Homogentisate 1,2-dioxygenase.
 
 0.959
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.902
FAH
Fumarylacetoacetase.
 
  
 0.891
GOT1
Aspartate aminotransferase.
  
 
 0.710
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
  
 
 0.703
PCCB
Propionyl-CoA carboxylase subunit beta.
  
 
 0.703
AADAT
Aminoadipate aminotransferase.
  
 
 0.678
HPD
4-hydroxyphenylpyruvate dioxygenase.
  
  
0.675
ENSOCUP00000036166
Aspartate aminotransferase.
  
 
 0.612
GOT2
Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).
  
 
 0.612
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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