GIGYF2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

GIGYF2

GRB10 interacting GYF protein 2. (1287 aa)

Predicted Functional Partners:

EIF4E2

0.992

DDX6

0.898

GRB10

0.856

TNRC6C

0.802

QRICH1

0.730

EIF4E

0.705

ASCC3

0.686

FBXO7

0.679

EIF4G1

0.676

PLA2G6

0.655

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCC3	DDX6	ENSOCUP00000002406	ENSOCUP00000005068	Activating signal cointegrator 1 complex subunit 3.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.423
ASCC3	GIGYF2	ENSOCUP00000002406	ENSOCUP00000001715	Activating signal cointegrator 1 complex subunit 3.	GRB10 interacting GYF protein 2.	0.686
DDX6	ASCC3	ENSOCUP00000005068	ENSOCUP00000002406	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Activating signal cointegrator 1 complex subunit 3.	0.423
DDX6	EIF4E	ENSOCUP00000005068	ENSOCUP00000032078	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	0.870
DDX6	EIF4E2	ENSOCUP00000005068	ENSOCUP00000042165	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	0.474
DDX6	EIF4G1	ENSOCUP00000005068	ENSOCUP00000032992	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	0.784
DDX6	GIGYF2	ENSOCUP00000005068	ENSOCUP00000001715	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	GRB10 interacting GYF protein 2.	0.898
DDX6	TNRC6C	ENSOCUP00000005068	ENSOCUP00000029587	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	Trinucleotide repeat containing adaptor 6C.	0.699
EIF4E	DDX6	ENSOCUP00000032078	ENSOCUP00000005068	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.870
EIF4E	EIF4G1	ENSOCUP00000032078	ENSOCUP00000032992	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	0.999
EIF4E	GIGYF2	ENSOCUP00000032078	ENSOCUP00000001715	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	GRB10 interacting GYF protein 2.	0.705
EIF4E	TNRC6C	ENSOCUP00000032078	ENSOCUP00000029587	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	Trinucleotide repeat containing adaptor 6C.	0.430
EIF4E2	DDX6	ENSOCUP00000042165	ENSOCUP00000005068	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.474
EIF4E2	EIF4G1	ENSOCUP00000042165	ENSOCUP00000032992	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	0.729
EIF4E2	GIGYF2	ENSOCUP00000042165	ENSOCUP00000001715	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	GRB10 interacting GYF protein 2.	0.992
EIF4G1	DDX6	ENSOCUP00000032992	ENSOCUP00000005068	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.784
EIF4G1	EIF4E	ENSOCUP00000032992	ENSOCUP00000032078	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	0.999
EIF4G1	EIF4E2	ENSOCUP00000032992	ENSOCUP00000042165	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.	0.729
EIF4G1	FBXO7	ENSOCUP00000032992	ENSOCUP00000035034	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	F-box domain-containing protein.	0.580
EIF4G1	GIGYF2	ENSOCUP00000032992	ENSOCUP00000001715	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	GRB10 interacting GYF protein 2.	0.676