Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGI3Leucine rich repeat LGI family member 3. (546 aa)    
Predicted Functional Partners:
ADAM23
ADAM metallopeptidase domain 23.
   
 
 0.805
ADAM22
ADAM metallopeptidase domain 22.
   
 
 0.778
ANKRD39
Ankyrin repeat domain 39.
    
 0.764
ADAM11
ADAM metallopeptidase domain 11.
   
 
 0.756
KCTD9
Potassium channel tetramerization domain containing 9.
      
 0.674
MTUS1
Microtubule associated scaffold protein 1.
    
 
 0.664
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
   
  
 0.662
CHMP7
Charged multivesicular body protein 7.
      
 0.543
FGF18
Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family.
    
 0.525
FEM1C
Fem-1 homolog C.
    
 0.521
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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