TBX18 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

TBX18

T-box transcription factor 18. (612 aa)

Predicted Functional Partners:

TCF21

0.821

SHOX2

0.809

WT1

0.798

NKX2-5

0.779

HCN4

0.758

ISL1

0.722

TNNT2

0.715

GATA4

0.594

ALDH1A2

0.590

MYL2

0.590

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	TBX18	ENSOCUP00000014561	ENSOCUP00000001753	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	T-box transcription factor 18.	0.590
ALDH1A2	TCF21	ENSOCUP00000014561	ENSOCUP00000015251	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Transcription factor 21.	0.583
ALDH1A2	WT1	ENSOCUP00000014561	ENSOCUP00000005099	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	WT1 transcription factor.	0.512
GATA4	HCN4	ENSOCUP00000001897	ENSOCUP00000015489	GATA binding protein 4.	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	0.530
GATA4	ISL1	ENSOCUP00000001897	ENSOCUP00000020036	GATA binding protein 4.	ISL LIM homeobox 1.	0.892
GATA4	MYL2	ENSOCUP00000001897	ENSOCUP00000028408	GATA binding protein 4.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.713
GATA4	NKX2-5	ENSOCUP00000001897	ENSOCUP00000000038	GATA binding protein 4.	NK2 homeobox 5.	0.995
GATA4	SHOX2	ENSOCUP00000001897	ENSOCUP00000027155	GATA binding protein 4.	Short stature homeobox 2.	0.410
GATA4	TBX18	ENSOCUP00000001897	ENSOCUP00000001753	GATA binding protein 4.	T-box transcription factor 18.	0.594
GATA4	TCF21	ENSOCUP00000001897	ENSOCUP00000015251	GATA binding protein 4.	Transcription factor 21.	0.559
GATA4	TNNT2	ENSOCUP00000001897	ENSOCUP00000018870	GATA binding protein 4.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.759
GATA4	WT1	ENSOCUP00000001897	ENSOCUP00000005099	GATA binding protein 4.	WT1 transcription factor.	0.792
HCN4	GATA4	ENSOCUP00000015489	ENSOCUP00000001897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	GATA binding protein 4.	0.530
HCN4	ISL1	ENSOCUP00000015489	ENSOCUP00000020036	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	ISL LIM homeobox 1.	0.684
HCN4	MYL2	ENSOCUP00000015489	ENSOCUP00000028408	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.712
HCN4	NKX2-5	ENSOCUP00000015489	ENSOCUP00000000038	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	NK2 homeobox 5.	0.751
HCN4	SHOX2	ENSOCUP00000015489	ENSOCUP00000027155	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	Short stature homeobox 2.	0.759
HCN4	TBX18	ENSOCUP00000015489	ENSOCUP00000001753	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	T-box transcription factor 18.	0.758
HCN4	TNNT2	ENSOCUP00000015489	ENSOCUP00000018870	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.754
ISL1	GATA4	ENSOCUP00000020036	ENSOCUP00000001897	ISL LIM homeobox 1.	GATA binding protein 4.	0.892