Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPP2Uncharacterized protein. (142 aa)    
Predicted Functional Partners:
APOM
Apolipoprotein M.
   
  
 0.768
FGA
Fibrinogen alpha chain.
   
  
 0.756
AHSG
Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family.
   
  
 0.748
CDC37L1
Cell division cycle 37 like 1.
     
 0.737
CPB2
Carboxypeptidase B2.
   
  
 0.734
HGD
Homogentisate 1,2-dioxygenase.
   
    0.680
ALG11
ALG11 alpha-1,2-mannosyltransferase.
   
  
 0.645
USP40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
    
 
 0.629
GC
Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
   
  
 0.625
IGFBP1
Insulin like growth factor binding protein 1.
   
 
  0.617
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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