Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRP4LDL receptor related protein 4. (1899 aa)    
Predicted Functional Partners:
MUSK
Receptor protein-tyrosine kinase.
   
 0.991
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.893
SOST
Sclerostin.
    
 0.770
DAB2
DAB adaptor protein 2.
    
 0.725
DKK1
Dickkopf-like protein 1.
    
 0.697
PTCH1
Patched 1.
   
 0.692
PTCH2
Patched 2.
   
 0.680
TG
COesterase domain-containing protein.
     
 0.678
WNT7A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.660
PCSK9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.652
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.