GTF2I protein (Oryctolagus cuniculus) - STRING interaction network

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Score

GTF2I

General transcription factor IIi. (997 aa)

Predicted Functional Partners:

BTK

0.925

PRKG1

0.899

PRKG2

0.891

ZMYM3

0.860

USF1

0.844

HDAC3

0.821

PCNT

0.785

HDAC2

0.765

ZMYM2

0.733

RELCH

0.725

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	GTF2I	ENSOCUP00000009153	ENSOCUP00000001789	Tyrosine-protein kinase.	General transcription factor IIi.	0.925
GTF2I	BTK	ENSOCUP00000001789	ENSOCUP00000009153	General transcription factor IIi.	Tyrosine-protein kinase.	0.925
GTF2I	HDAC2	ENSOCUP00000001789	ENSOCUP00000040151	General transcription factor IIi.	Histone deacetylase 2.	0.765
GTF2I	HDAC3	ENSOCUP00000001789	ENSOCUP00000007738	General transcription factor IIi.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.821
GTF2I	PCNT	ENSOCUP00000001789	ENSOCUP00000004167	General transcription factor IIi.	Pericentrin.	0.785
GTF2I	PRKG1	ENSOCUP00000001789	ENSOCUP00000031575	General transcription factor IIi.	cGMP-dependent protein kinase 1; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-s [...]	0.899
GTF2I	PRKG2	ENSOCUP00000001789	ENSOCUP00000007323	General transcription factor IIi.	cGMP-dependent protein kinase.	0.891
GTF2I	RELCH	ENSOCUP00000001789	ENSOCUP00000031897	General transcription factor IIi.	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing.	0.725
GTF2I	USF1	ENSOCUP00000001789	ENSOCUP00000043874	General transcription factor IIi.	Upstream stimulatory factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. Regulates the expression of the surfactant protein- A (SP-A) gene.	0.844
GTF2I	ZMYM2	ENSOCUP00000001789	ENSOCUP00000014688	General transcription factor IIi.	Zinc finger MYM-type containing 2.	0.733
GTF2I	ZMYM3	ENSOCUP00000001789	ENSOCUP00000020325	General transcription factor IIi.	Zinc finger MYM-type containing 3.	0.860
HDAC2	GTF2I	ENSOCUP00000040151	ENSOCUP00000001789	Histone deacetylase 2.	General transcription factor IIi.	0.765
HDAC2	HDAC3	ENSOCUP00000040151	ENSOCUP00000007738	Histone deacetylase 2.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.948
HDAC2	ZMYM2	ENSOCUP00000040151	ENSOCUP00000014688	Histone deacetylase 2.	Zinc finger MYM-type containing 2.	0.887
HDAC2	ZMYM3	ENSOCUP00000040151	ENSOCUP00000020325	Histone deacetylase 2.	Zinc finger MYM-type containing 3.	0.860
HDAC3	GTF2I	ENSOCUP00000007738	ENSOCUP00000001789	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	General transcription factor IIi.	0.821
HDAC3	HDAC2	ENSOCUP00000007738	ENSOCUP00000040151	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.948
PCNT	GTF2I	ENSOCUP00000004167	ENSOCUP00000001789	Pericentrin.	General transcription factor IIi.	0.785
PRKG1	GTF2I	ENSOCUP00000031575	ENSOCUP00000001789	cGMP-dependent protein kinase 1; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-s [...]	General transcription factor IIi.	0.899
PRKG1	PRKG2	ENSOCUP00000031575	ENSOCUP00000007323	cGMP-dependent protein kinase 1; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-s [...]	cGMP-dependent protein kinase.	0.851