Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NR1H3Liver X receptor alpha. (447 aa)    
Predicted Functional Partners:
ABCA1
ATP binding cassette subfamily A member 1.
   
 0.987
RXRB
Retinoid X receptor beta.
  
0.972
RXRG
Retinoid X receptor gamma.
   
 0.961
NCOR1
Nuclear receptor corepressor 1.
    
 0.902
NCOA1
Nuclear receptor coactivator.
    
 0.898
PPARA
Peroxisome proliferator activated receptor alpha.
    
0.871
NCOA2
Nuclear receptor coactivator.
    
 0.869
PSME3
Proteasome activator subunit 3.
   
  0.861
OGT
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue. Acts on cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Probably by glycosyla [...]
    
  0.857
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
 0.856
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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