Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MADDMAP kinase activating death domain. (1646 aa)    
Predicted Functional Partners:
RAB27B
RAB27B, member RAS oncogene family.
     
 0.815
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.809
SYT6
Synaptotagmin 6.
    
   0.762
RAB27A
RAB27A, member RAS oncogene family.
     
 0.738
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.653
DENND5A
DENN domain containing 5A.
    
 
 0.652
DENND5B
DENN domain containing 5B.
    
 
 0.642
PIBF1
Progesterone immunomodulatory binding factor 1.
      
 0.627
DENND1A
DENN domain containing 1A.
    
 
 0.610
G1TFT8_RABIT
Death domain-containing protein.
      
 0.608
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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