MYBPC3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

MYBPC3

Myosin binding protein C, cardiac. (1250 aa)

Predicted Functional Partners:

MYL3

0.971

MYL2

0.955

MYH7

0.950

TNNT2

0.924

ACTN2

0.864

TCAP

0.862

MYBPC1

0.851

MYL4

0.849

MYLPF

0.829

TPM1

0.820

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	MYBPC1	ENSOCUP00000047925	ENSOCUP00000017406	Actinin alpha 2.	Myosin binding protein C, slow type.	0.740
ACTN2	MYBPC3	ENSOCUP00000047925	ENSOCUP00000001825	Actinin alpha 2.	Myosin binding protein C, cardiac.	0.864
ACTN2	MYH7	ENSOCUP00000047925	ENSOCUP00000021291	Actinin alpha 2.	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.904
ACTN2	MYL2	ENSOCUP00000047925	ENSOCUP00000028408	Actinin alpha 2.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.872
ACTN2	MYL3	ENSOCUP00000047925	ENSOCUP00000029317	Actinin alpha 2.	Myosin light chain 3.	0.840
ACTN2	MYL4	ENSOCUP00000047925	ENSOCUP00000037806	Actinin alpha 2.	Myosin light chain 4.	0.704
ACTN2	MYLPF	ENSOCUP00000047925	ENSOCUP00000015491	Actinin alpha 2.	Myosin regulatory light chain 2, skeletal muscle isoform type 2.	0.743
ACTN2	TCAP	ENSOCUP00000047925	ENSOCUP00000021853	Actinin alpha 2.	Titin-cap.	0.858
ACTN2	TNNT2	ENSOCUP00000047925	ENSOCUP00000018870	Actinin alpha 2.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.902
ACTN2	TPM1	ENSOCUP00000047925	ENSOCUP00000012137	Actinin alpha 2.	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family.	0.822
MYBPC1	ACTN2	ENSOCUP00000017406	ENSOCUP00000047925	Myosin binding protein C, slow type.	Actinin alpha 2.	0.740
MYBPC1	MYBPC3	ENSOCUP00000017406	ENSOCUP00000001825	Myosin binding protein C, slow type.	Myosin binding protein C, cardiac.	0.851
MYBPC1	MYH7	ENSOCUP00000017406	ENSOCUP00000021291	Myosin binding protein C, slow type.	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.641
MYBPC1	MYL2	ENSOCUP00000017406	ENSOCUP00000028408	Myosin binding protein C, slow type.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.841
MYBPC1	MYL3	ENSOCUP00000017406	ENSOCUP00000029317	Myosin binding protein C, slow type.	Myosin light chain 3.	0.797
MYBPC1	MYL4	ENSOCUP00000017406	ENSOCUP00000037806	Myosin binding protein C, slow type.	Myosin light chain 4.	0.748
MYBPC1	MYLPF	ENSOCUP00000017406	ENSOCUP00000015491	Myosin binding protein C, slow type.	Myosin regulatory light chain 2, skeletal muscle isoform type 2.	0.964
MYBPC1	TCAP	ENSOCUP00000017406	ENSOCUP00000021853	Myosin binding protein C, slow type.	Titin-cap.	0.640
MYBPC1	TNNT2	ENSOCUP00000017406	ENSOCUP00000018870	Myosin binding protein C, slow type.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.636
MYBPC1	TPM1	ENSOCUP00000017406	ENSOCUP00000012137	Myosin binding protein C, slow type.	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family.	0.563