Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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EMP3Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. (163 aa)    
Predicted Functional Partners:
TGFBR2
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
     
 0.873
S100A4
Protein S100; Belongs to the S-100 family.
   
  
 0.767
LGALS1
Galectin.
   
  
 0.764
TMEM143
Transmembrane protein 143.
      
 0.673
RHAG
Rh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.560
EPB42
Erythrocyte membrane protein band 4.2.
   
  
 0.548
MBOAT2
Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family.
      
 0.536
FXYD5
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
   
    0.534
IFFO1
Uncharacterized protein.
  
   
 0.527
ZNF362
Zinc finger protein 362.
      
 0.522
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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