Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDUFAF4Uncharacterized protein. (175 aa)    
Predicted Functional Partners:
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3.
   
 0.992
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.
   
 0.984
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
    
 0.978
TIMMDC1
Translocase of inner mitochondrial membrane domain containing 1.
   
 0.976
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
    
 0.975
NDUFAF2
NADH:ubiquinone oxidoreductase complex assembly factor 2.
   
 0.942
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.921
ECSIT
ECSIT signalling integrator.
    
 0.920
NDUFS6
zf-CHCC domain-containing protein.
   
 
 0.920
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 0.918
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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