SUPT5H protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SUPT5H

Transcription elongation factor SPT5. (1083 aa)

Predicted Functional Partners:

SUPT4H1

0.999

SUPT6H

0.998

POLR2G

0.998

POLR2C

0.998

POLR2B

0.998

SUPT16H

0.997

POLR2F

0.997

POLR2J

0.996

POLR2H

0.995

RNGTT

0.992

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
POLR2B	POLR2C	ENSOCUP00000014066	ENSOCUP00000012875	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit C.	0.999
POLR2B	POLR2F	ENSOCUP00000014066	ENSOCUP00000010376	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit F.	0.999
POLR2B	POLR2G	ENSOCUP00000014066	ENSOCUP00000008180	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit G.	0.999
POLR2B	POLR2H	ENSOCUP00000014066	ENSOCUP00000006120	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
POLR2B	POLR2J	ENSOCUP00000014066	ENSOCUP00000016720	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit J.	0.999
POLR2B	RNGTT	ENSOCUP00000014066	ENSOCUP00000014680	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.765
POLR2B	SUPT16H	ENSOCUP00000014066	ENSOCUP00000009303	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.979
POLR2B	SUPT4H1	ENSOCUP00000014066	ENSOCUP00000022993	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.999
POLR2B	SUPT5H	ENSOCUP00000014066	ENSOCUP00000001861	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor SPT5.	0.998
POLR2B	SUPT6H	ENSOCUP00000014066	ENSOCUP00000000738	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.931
POLR2C	POLR2B	ENSOCUP00000012875	ENSOCUP00000014066	RNA polymerase II subunit C.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
POLR2C	POLR2F	ENSOCUP00000012875	ENSOCUP00000010376	RNA polymerase II subunit C.	RNA polymerase II subunit F.	0.999
POLR2C	POLR2G	ENSOCUP00000012875	ENSOCUP00000008180	RNA polymerase II subunit C.	RNA polymerase II subunit G.	0.999
POLR2C	POLR2H	ENSOCUP00000012875	ENSOCUP00000006120	RNA polymerase II subunit C.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
POLR2C	POLR2J	ENSOCUP00000012875	ENSOCUP00000016720	RNA polymerase II subunit C.	RNA polymerase II subunit J.	0.999
POLR2C	RNGTT	ENSOCUP00000012875	ENSOCUP00000014680	RNA polymerase II subunit C.	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.	0.839
POLR2C	SUPT16H	ENSOCUP00000012875	ENSOCUP00000009303	RNA polymerase II subunit C.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.980
POLR2C	SUPT4H1	ENSOCUP00000012875	ENSOCUP00000022993	RNA polymerase II subunit C.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.998
POLR2C	SUPT5H	ENSOCUP00000012875	ENSOCUP00000001861	RNA polymerase II subunit C.	Transcription elongation factor SPT5.	0.998
POLR2C	SUPT6H	ENSOCUP00000012875	ENSOCUP00000000738	RNA polymerase II subunit C.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.971