STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1353 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.847
BTK
Tyrosine-protein kinase.
   
 0.787
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.706
DNAJC17
DnaJ heat shock protein family (Hsp40) member C17.
      
 0.632
CACUL1
CDK2 associated cullin domain 1.
   
 0.602
LRRK1
Leucine rich repeat kinase 1.
    
 0.587
FSCB
Uncharacterized protein.
   
 0.556
GLT8D2
Glycosyltransferase 8 domain containing 2.
   
  
 0.544
KBTBD8
Uncharacterized protein.
      
 0.525
ABTB1
Ankyrin repeat and BTB domain containing 1.
   
 0.511
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.