Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARL1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)    
Predicted Functional Partners:
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.898
CCDC185
Coiled-coil domain containing 185.
      
 0.873
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
      
 0.773
ARFIP2
ADP ribosylation factor interacting protein 2.
    
 0.761
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 0.751
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
   
 0.749
STX16-NPEPL1
STX16-NPEPL1 readthrough (NMD candidate); Belongs to the syntaxin family.
    
 0.738
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 0.732
COG8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 0.719
GCC2
GRIP and coiled-coil domain containing 2.
   
 0.711
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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