VLDLR protein (Oryctolagus cuniculus) - STRING interaction network

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VLDLR

Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). (873 aa)

Predicted Functional Partners:

DAB1

0.995

RELN

0.987

PCSK9

0.973

APOB

0.948

ENSOCUP00000046066

0.929

ENSOCUP00000046526

0.929

MYLIP

0.887

PIK3CB

0.860

PIK3CD

0.860

PIK3CA

0.860

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	PCSK9	ENSOCUP00000004631	ENSOCUP00000046637	Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.912
APOB	VLDLR	ENSOCUP00000004631	ENSOCUP00000001926	Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.	Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).	0.948
DAB1	ENSOCUP00000046066	ENSOCUP00000044904	ENSOCUP00000046066	DAB adaptor protein 1.	EGF-like domain-containing protein.	0.725
DAB1	ENSOCUP00000046526	ENSOCUP00000044904	ENSOCUP00000046526	DAB adaptor protein 1.	Reelin domain-containing protein.	0.725
DAB1	PIK3CA	ENSOCUP00000044904	ENSOCUP00000026298	DAB adaptor protein 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.854
DAB1	PIK3CB	ENSOCUP00000044904	ENSOCUP00000004241	DAB adaptor protein 1.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.854
DAB1	PIK3CD	ENSOCUP00000044904	ENSOCUP00000021004	DAB adaptor protein 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.854
DAB1	RELN	ENSOCUP00000044904	ENSOCUP00000007831	DAB adaptor protein 1.	Uncharacterized protein.	0.884
DAB1	VLDLR	ENSOCUP00000044904	ENSOCUP00000001926	DAB adaptor protein 1.	Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).	0.995
ENSOCUP00000046066	DAB1	ENSOCUP00000046066	ENSOCUP00000044904	EGF-like domain-containing protein.	DAB adaptor protein 1.	0.725
ENSOCUP00000046066	ENSOCUP00000046526	ENSOCUP00000046066	ENSOCUP00000046526	EGF-like domain-containing protein.	Reelin domain-containing protein.	0.938
ENSOCUP00000046066	VLDLR	ENSOCUP00000046066	ENSOCUP00000001926	EGF-like domain-containing protein.	Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).	0.929
ENSOCUP00000046526	DAB1	ENSOCUP00000046526	ENSOCUP00000044904	Reelin domain-containing protein.	DAB adaptor protein 1.	0.725
ENSOCUP00000046526	ENSOCUP00000046066	ENSOCUP00000046526	ENSOCUP00000046066	Reelin domain-containing protein.	EGF-like domain-containing protein.	0.938
ENSOCUP00000046526	RELN	ENSOCUP00000046526	ENSOCUP00000007831	Reelin domain-containing protein.	Uncharacterized protein.	0.942
ENSOCUP00000046526	VLDLR	ENSOCUP00000046526	ENSOCUP00000001926	Reelin domain-containing protein.	Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).	0.929
MYLIP	PCSK9	ENSOCUP00000006918	ENSOCUP00000046637	Myosin regulatory light chain interacting protein.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.473
MYLIP	VLDLR	ENSOCUP00000006918	ENSOCUP00000001926	Myosin regulatory light chain interacting protein.	Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).	0.887
PCSK9	APOB	ENSOCUP00000046637	ENSOCUP00000004631	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.	0.912
PCSK9	MYLIP	ENSOCUP00000046637	ENSOCUP00000006918	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	Myosin regulatory light chain interacting protein.	0.473

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