Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIAA0355KIAA0355. (1070 aa)    
Predicted Functional Partners:
NCKAP1
NCK associated protein 1.
    
  0.737
PKNOX1
PBX/knotted 1 homeobox 1.
   
  
 0.720
PKNOX1-2
Uncharacterized protein.
   
  
 0.713
NCKAP1L
NCK associated protein 1 like.
    
  0.615
ABI1
Abl interactor 1.
    
  0.596
RHOG
Ras homolog family member G.
   
 
  0.578
ENSOCUP00000041442
Uncharacterized protein.
   
 
  0.578
DOCK4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
    
 0.563
BAIAP2L1
BAI1 associated protein 2 like 1.
     
  0.539
PAK2
Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]
     
  0.539
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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