CYP2U1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

CYP2U1

Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (548 aa)

Predicted Functional Partners:

ALDH3A2

0.889

PLA2G6

0.883

CYP2E1

0.878

PLA2G3

0.866

PLA2G4A

0.865

PLA2G4F

0.864

PLA2G4E

0.863

ALOX15B

0.857

PLA2G4B

0.857

PLA2G12B

0.857

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH3A2	CYP2E1	ENSOCUP00000039829	ENSOCUP00000043752	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	0.958
ALDH3A2	CYP2U1	ENSOCUP00000039829	ENSOCUP00000001967	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.889
ALOX15B	CYP2E1	ENSOCUP00000008906	ENSOCUP00000043752	Arachidonate 15-lipoxygenase type B.	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	0.860
ALOX15B	CYP2U1	ENSOCUP00000008906	ENSOCUP00000001967	Arachidonate 15-lipoxygenase type B.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.857
ALOX15B	PLA2G12B	ENSOCUP00000008906	ENSOCUP00000013787	Arachidonate 15-lipoxygenase type B.	Phospholipase A2 group XIIB.	0.851
ALOX15B	PLA2G3	ENSOCUP00000008906	ENSOCUP00000003567	Arachidonate 15-lipoxygenase type B.	Phospholipase A2 group III.	0.876
ALOX15B	PLA2G4A	ENSOCUP00000008906	ENSOCUP00000012590	Arachidonate 15-lipoxygenase type B.	Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity).	0.908
ALOX15B	PLA2G4B	ENSOCUP00000008906	ENSOCUP00000010309	Arachidonate 15-lipoxygenase type B.	Phospholipase A2.	0.918
ALOX15B	PLA2G4E	ENSOCUP00000008906	ENSOCUP00000032066	Arachidonate 15-lipoxygenase type B.	Phospholipase A2.	0.914
ALOX15B	PLA2G4F	ENSOCUP00000008906	ENSOCUP00000034665	Arachidonate 15-lipoxygenase type B.	Phospholipase A2.	0.924
ALOX15B	PLA2G6	ENSOCUP00000008906	ENSOCUP00000005319	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.862
CYP2E1	ALDH3A2	ENSOCUP00000043752	ENSOCUP00000039829	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.958
CYP2E1	ALOX15B	ENSOCUP00000043752	ENSOCUP00000008906	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Arachidonate 15-lipoxygenase type B.	0.860
CYP2E1	CYP2U1	ENSOCUP00000043752	ENSOCUP00000001967	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.878
CYP2E1	PLA2G12B	ENSOCUP00000043752	ENSOCUP00000013787	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Phospholipase A2 group XIIB.	0.884
CYP2E1	PLA2G3	ENSOCUP00000043752	ENSOCUP00000003567	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Phospholipase A2 group III.	0.876
CYP2E1	PLA2G4A	ENSOCUP00000043752	ENSOCUP00000012590	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity).	0.856
CYP2E1	PLA2G4B	ENSOCUP00000043752	ENSOCUP00000010309	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Phospholipase A2.	0.851
CYP2E1	PLA2G4E	ENSOCUP00000043752	ENSOCUP00000032066	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Phospholipase A2.	0.851
CYP2E1	PLA2G4F	ENSOCUP00000043752	ENSOCUP00000034665	Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.	Phospholipase A2.	0.876