Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NUAK2NUAK family kinase 2. (618 aa)    
Predicted Functional Partners:
ARHGEF17
Rho guanine nucleotide exchange factor 17.
      
 0.737
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
   0.696
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
   
  
 0.645
USP9X
Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family.
    
 
 0.623
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
    
 
 0.609
FBXW11
F-box and WD repeat domain containing 11.
    
   0.608
AMOTL2
Angiomotin like 2.
   
  
 0.592
MED20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.558
FJX1
Four-jointed box kinase 1.
      
 0.529
CRIM1
Cysteine rich transmembrane BMP regulator 1.
      
 0.528
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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