ZNF609 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZNF609

Zinc finger protein 609. (1411 aa)

Predicted Functional Partners:

SHPRH

0.820

HIPK3

0.605

ZKSCAN1

0.598

EIF4G2

0.568

MBNL3

0.562

AGO1

0.554

AGO2

0.542

MTO1

0.540

FBXW7

0.529

CCDC66

0.501

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSOCUP00000019687	ENSOCUP00000030946	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-2; Belongs to the argonaute family.	0.955
AGO1	HIPK3	ENSOCUP00000019687	ENSOCUP00000025303	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Homeodomain interacting protein kinase 3.	0.460
AGO1	ZNF609	ENSOCUP00000019687	ENSOCUP00000002005	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Zinc finger protein 609.	0.554
AGO2	AGO1	ENSOCUP00000030946	ENSOCUP00000019687	Protein argonaute-2; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.955
AGO2	HIPK3	ENSOCUP00000030946	ENSOCUP00000025303	Protein argonaute-2; Belongs to the argonaute family.	Homeodomain interacting protein kinase 3.	0.424
AGO2	ZNF609	ENSOCUP00000030946	ENSOCUP00000002005	Protein argonaute-2; Belongs to the argonaute family.	Zinc finger protein 609.	0.542
CCDC66	ZNF609	ENSOCUP00000011408	ENSOCUP00000002005	Coiled-coil domain containing 66.	Zinc finger protein 609.	0.501
EIF4G2	ZNF609	ENSOCUP00000046928	ENSOCUP00000002005	Eukaryotic translation initiation factor 4 gamma 2; Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. Belongs to the eukaryotic initiation factor 4G family.	Zinc finger protein 609.	0.568
FBXW7	SHPRH	ENSOCUP00000007292	ENSOCUP00000009446	F-box and WD repeat domain containing 7.	SNF2 histone linker PHD RING helicase.	0.552
FBXW7	ZNF609	ENSOCUP00000007292	ENSOCUP00000002005	F-box and WD repeat domain containing 7.	Zinc finger protein 609.	0.529
HIPK3	AGO1	ENSOCUP00000025303	ENSOCUP00000019687	Homeodomain interacting protein kinase 3.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.460
HIPK3	AGO2	ENSOCUP00000025303	ENSOCUP00000030946	Homeodomain interacting protein kinase 3.	Protein argonaute-2; Belongs to the argonaute family.	0.424
HIPK3	MTO1	ENSOCUP00000025303	ENSOCUP00000033233	Homeodomain interacting protein kinase 3.	GIDA_assoc domain-containing protein.	0.514
HIPK3	ZKSCAN1	ENSOCUP00000025303	ENSOCUP00000013172	Homeodomain interacting protein kinase 3.	Zinc finger with KRAB and SCAN domains 1.	0.514
HIPK3	ZNF609	ENSOCUP00000025303	ENSOCUP00000002005	Homeodomain interacting protein kinase 3.	Zinc finger protein 609.	0.605
MBNL3	ZNF609	ENSOCUP00000039200	ENSOCUP00000002005	Muscleblind like splicing regulator 3.	Zinc finger protein 609.	0.562
MTO1	HIPK3	ENSOCUP00000033233	ENSOCUP00000025303	GIDA_assoc domain-containing protein.	Homeodomain interacting protein kinase 3.	0.514
MTO1	ZNF609	ENSOCUP00000033233	ENSOCUP00000002005	GIDA_assoc domain-containing protein.	Zinc finger protein 609.	0.540
SHPRH	FBXW7	ENSOCUP00000009446	ENSOCUP00000007292	SNF2 histone linker PHD RING helicase.	F-box and WD repeat domain containing 7.	0.552
SHPRH	ZNF609	ENSOCUP00000009446	ENSOCUP00000002005	SNF2 histone linker PHD RING helicase.	Zinc finger protein 609.	0.820