Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSMEM2Leucine rich single-pass membrane protein 2. (244 aa)    
Predicted Functional Partners:
KLHL34
Kelch like family member 34.
      
 0.758
ADPRHL1
ADP-ribosylhydrolase like 1.
      
 0.679
SPACA1
Sperm acrosome associated 1.
    
   0.588
ITIH1
Uncharacterized protein.
      
 0.542
ABCB6
ATP binding cassette subfamily B member 6 (Langereis blood group).
      
 0.490
WDR47
WD repeat domain 47.
      
 0.465
LRRK1
Leucine rich repeat kinase 1.
      
 0.463
APOM
Apolipoprotein M.
      
 0.436
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
      
 0.426
MYT1L
Myelin transcription factor 1 like.
      
 0.410
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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