STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN4Nectin cell adhesion molecule 4. (509 aa)    
Predicted Functional Partners:
NECTIN1
Nectin cell adhesion molecule 1.
    
0.979
NECTIN3
Nectin cell adhesion molecule 3.
    
0.941
PARD3
Par-3 family cell polarity regulator.
    
  0.903
AFDN
Afadin, adherens junction formation factor.
   
 0.762
SLAMF1
Signaling lymphocytic activation molecule family member 1.
   
  
 0.661
TMEM164
Transmembrane protein 164.
   
  
 0.651
MYBPH
Myosin binding protein H.
   
  
 0.638
LOC100341359
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
    
 0.571
MCAM
Melanoma cell adhesion molecule.
  
 
 0.507
SERPINA4
SERPIN domain-containing protein; Belongs to the serpin family.
   
 
 0.496
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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