Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN4Nectin cell adhesion molecule 4. (509 aa)    
Predicted Functional Partners:
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.966
AFDN
Afadin, adherens junction formation factor.
    
 0.922
NECTIN3
Nectin cell adhesion molecule 3.
    
0.878
PARD3
Par-3 family cell polarity regulator.
    
 0.878
NECTIN2
Nectin cell adhesion molecule 2.
    
0.877
EIF2B1
Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
   0.769
EIF2B2
Translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
   0.753
EIF2B4
Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
   0.731
ENAH
ENAH actin regulator.
    
   0.729
EIF2B3
Eukaryotic translation initiation factor 2B subunit gamma.
    
   0.678
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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