Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SMYD5SMYD family member 5. (421 aa)    
Predicted Functional Partners:
SMYD4
SET and MYND domain containing 4.
      
 0.886
SMYD1
SET and MYND domain containing 1.
      
 0.825
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 0.741
KMT2E
Lysine methyltransferase 2E.
    
 0.668
SMYD3
SET and MYND domain containing 3.
      
0.654
SETD2
Uncharacterized protein.
     
 0.637
KDM6B
Lysine demethylase 6B.
   
 0.635
KMT5B
Lysine methyltransferase 5B.
     
 0.634
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
   
 
 0.611
SETD3
Protein-histidine N-methyltransferase.
   
 
 0.593
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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