STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRM4Glutamate metabotropic receptor 4. (1050 aa)    
Predicted Functional Partners:
GRM1
Glutamate metabotropic receptor 1.
   
 
0.922
GRM8
Glutamate metabotropic receptor 8.
  
  
0.917
GRM6
Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
  
 
0.904
LOC100346323
Uncharacterized protein.
    
  0.745
GNA12
G protein subunit alpha 12.
   
  0.698
GNA13
G protein subunit alpha 13.
    
  0.698
AGT
Angiotensinogen; Belongs to the serpin family.
   
 
  0.675
AVP
Uncharacterized protein.
   
 
  0.659
GNAS
GNAS complex locus.
     
 0.655
GRM2
Glutamate metabotropic receptor 2.
  
0.650
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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