Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (462 aa)    
Predicted Functional Partners:
MTHFS
5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate. It can also use 5-formyltetrahydropteroic acid (5-CHO-H(4)Pte) and 5-formyltetrahydropteroylhistidine (5-CHO- H(4)PteHis) as substrate; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
     
 0.914
NOP56
NOP56 ribonucleoprotein.
   
    0.893
UTP15
UTP15 small subunit processome component.
   
    0.889
NIPSNAP2
Nipsnap homolog 2.
   
    0.822
NIPSNAP1
Nipsnap homolog 1.
   
    0.822
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
   
 
 0.808
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
 0.791
G1T572_RABIT
Ribosomal_L7Ae domain-containing protein.
   
    0.755
SNU13
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.755
ENSOCUP00000028949
Ribosomal_L7Ae domain-containing protein.
   
    0.755
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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