| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APOA1 | APOB | ENSOCUP00000009241 | ENSOCUP00000004631 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.999 |
| APOA1 | CD36 | ENSOCUP00000009241 | ENSOCUP00000002156 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | CD36 molecule; Belongs to the CD36 family. | 0.905 |
| APOA1 | PPARG | ENSOCUP00000009241 | ENSOCUP00000043929 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.601 |
| APOB | APOA1 | ENSOCUP00000004631 | ENSOCUP00000009241 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.999 |
| APOB | CD36 | ENSOCUP00000004631 | ENSOCUP00000002156 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | CD36 molecule; Belongs to the CD36 family. | 0.949 |
| APOB | FYN | ENSOCUP00000004631 | ENSOCUP00000013559 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Tyrosine-protein kinase. | 0.476 |
| APOB | PPARG | ENSOCUP00000004631 | ENSOCUP00000043929 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.683 |
| APOB | TLR4 | ENSOCUP00000004631 | ENSOCUP00000001909 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.623 |
| CD36 | APOA1 | ENSOCUP00000002156 | ENSOCUP00000009241 | CD36 molecule; Belongs to the CD36 family. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.905 |
| CD36 | APOB | ENSOCUP00000002156 | ENSOCUP00000004631 | CD36 molecule; Belongs to the CD36 family. | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.949 |
| CD36 | FYN | ENSOCUP00000002156 | ENSOCUP00000013559 | CD36 molecule; Belongs to the CD36 family. | Tyrosine-protein kinase. | 0.878 |
| CD36 | LYN | ENSOCUP00000002156 | ENSOCUP00000002661 | CD36 molecule; Belongs to the CD36 family. | Tyrosine-protein kinase. | 0.955 |
| CD36 | PPARG | ENSOCUP00000002156 | ENSOCUP00000043929 | CD36 molecule; Belongs to the CD36 family. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.897 |
| CD36 | THBS1 | ENSOCUP00000002156 | ENSOCUP00000003290 | CD36 molecule; Belongs to the CD36 family. | Thrombospondin 1. | 0.967 |
| CD36 | THBS2 | ENSOCUP00000002156 | ENSOCUP00000023287 | CD36 molecule; Belongs to the CD36 family. | Thrombospondin 2. | 0.916 |
| CD36 | THBS3 | ENSOCUP00000002156 | ENSOCUP00000008645 | CD36 molecule; Belongs to the CD36 family. | Thrombospondin 3. | 0.879 |
| CD36 | THBS4 | ENSOCUP00000002156 | ENSOCUP00000007987 | CD36 molecule; Belongs to the CD36 family. | Thrombospondin 4. | 0.887 |
| CD36 | TLR4 | ENSOCUP00000002156 | ENSOCUP00000001909 | CD36 molecule; Belongs to the CD36 family. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.895 |
| FYN | APOB | ENSOCUP00000013559 | ENSOCUP00000004631 | Tyrosine-protein kinase. | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.476 |
| FYN | CD36 | ENSOCUP00000013559 | ENSOCUP00000002156 | Tyrosine-protein kinase. | CD36 molecule; Belongs to the CD36 family. | 0.878 |