STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEF8Differentially expressed in FDCP 8 homolog. (446 aa)    
Predicted Functional Partners:
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
      
 0.805
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1.
   
  
 0.676
TREML2
Triggering receptor expressed on myeloid cells like 2.
   
  
 0.666
NDEL1
Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...]
    
 
 0.637
ABI3
ABI family member 3.
      
 0.617
CLUAP1
Clusterin associated protein 1.
      
 0.616
RRBP1
Ribosome binding protein 1.
      
 0.583
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
  
 0.580
FAM98A
Family with sequence similarity 98 member A.
    
 
 0.555
RIN3
Ras and Rab interactor 3.
   
  
 0.550
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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