Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRCH4Leucine rich repeats and calponin homology domain containing 4. (685 aa)    
Predicted Functional Partners:
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
 
 0.926
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
   
   0.826
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
  
 
 
0.681
SMTNL1
Smoothelin like 1.
      
 0.596
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.
   
  
 0.573
ANKRD54
ANK_REP_REGION domain-containing protein.
    
 0.558
ANKRD46
Ankyrin repeat domain 46.
    
 0.552
AGFG2
ArfGAP with FG repeats 2.
      
 0.549
ASB8
Ankyrin repeat and SOCS box containing 8.
    
 0.548
U3KN95_RABIT
Uncharacterized protein.
  
   0.522
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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