ROBO1 protein (Oryctolagus cuniculus) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

ROBO1

Roundabout guidance receptor 1. (1651 aa)

Predicted Functional Partners:

SLIT2

0.998

SLIT1

0.987

SRGAP1

0.982

SLIT3

0.979

SRGAP2

0.953

ABL1

0.951

ROBO3

0.942

G1U2H9_RABIT

0.935

NCK2

0.931

PAK2

0.925

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	NCK2	ENSOCUP00000038489	ENSOCUP00000023883	Tyrosine-protein kinase.	Cytoplasmic protein.	0.418
ABL1	ROBO1	ENSOCUP00000038489	ENSOCUP00000002194	Tyrosine-protein kinase.	Roundabout guidance receptor 1.	0.951
ABL1	SLIT1	ENSOCUP00000038489	ENSOCUP00000003192	Tyrosine-protein kinase.	Slit guidance ligand 1.	0.459
ABL1	SLIT2	ENSOCUP00000038489	ENSOCUP00000029723	Tyrosine-protein kinase.	Slit guidance ligand 2.	0.466
ABL1	SLIT3	ENSOCUP00000038489	ENSOCUP00000046495	Tyrosine-protein kinase.	Slit guidance ligand 3.	0.461
G1U2H9_RABIT	ROBO1	ENSOCUP00000023578	ENSOCUP00000002194	F-BAR domain-containing protein.	Roundabout guidance receptor 1.	0.935
G1U2H9_RABIT	SRGAP1	ENSOCUP00000023578	ENSOCUP00000008355	F-BAR domain-containing protein.	SLIT-ROBO Rho GTPase activating protein 1.	0.916
G1U2H9_RABIT	SRGAP2	ENSOCUP00000023578	ENSOCUP00000010482	F-BAR domain-containing protein.	Uncharacterized protein.	0.917
NCK2	ABL1	ENSOCUP00000023883	ENSOCUP00000038489	Cytoplasmic protein.	Tyrosine-protein kinase.	0.418
NCK2	PAK2	ENSOCUP00000023883	ENSOCUP00000007111	Cytoplasmic protein.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.973
NCK2	ROBO1	ENSOCUP00000023883	ENSOCUP00000002194	Cytoplasmic protein.	Roundabout guidance receptor 1.	0.931
PAK2	NCK2	ENSOCUP00000007111	ENSOCUP00000023883	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	Cytoplasmic protein.	0.973
PAK2	ROBO1	ENSOCUP00000007111	ENSOCUP00000002194	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	Roundabout guidance receptor 1.	0.925
PAK2	SRGAP1	ENSOCUP00000007111	ENSOCUP00000008355	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	SLIT-ROBO Rho GTPase activating protein 1.	0.437
ROBO1	ABL1	ENSOCUP00000002194	ENSOCUP00000038489	Roundabout guidance receptor 1.	Tyrosine-protein kinase.	0.951
ROBO1	G1U2H9_RABIT	ENSOCUP00000002194	ENSOCUP00000023578	Roundabout guidance receptor 1.	F-BAR domain-containing protein.	0.935
ROBO1	NCK2	ENSOCUP00000002194	ENSOCUP00000023883	Roundabout guidance receptor 1.	Cytoplasmic protein.	0.931
ROBO1	PAK2	ENSOCUP00000002194	ENSOCUP00000007111	Roundabout guidance receptor 1.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.925
ROBO1	ROBO3	ENSOCUP00000002194	ENSOCUP00000002281	Roundabout guidance receptor 1.	Roundabout guidance receptor 3.	0.942
ROBO1	SLIT1	ENSOCUP00000002194	ENSOCUP00000003192	Roundabout guidance receptor 1.	Slit guidance ligand 1.	0.987