| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTRC | CAND1 | ENSOCUP00000049583 | ENSOCUP00000004347 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Cullin associated and neddylation dissociated 1. | 0.484 |
| BTRC | CUL1 | ENSOCUP00000049583 | ENSOCUP00000002198 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Cullin 1; Belongs to the cullin family. | 0.995 |
| BTRC | FBXL3 | ENSOCUP00000049583 | ENSOCUP00000010224 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box and leucine rich repeat protein 3. | 0.539 |
| BTRC | FBXW11 | ENSOCUP00000049583 | ENSOCUP00000016400 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box and WD repeat domain containing 11. | 0.998 |
| BTRC | FBXW7 | ENSOCUP00000049583 | ENSOCUP00000007292 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box and WD repeat domain containing 7. | 0.887 |
| BTRC | NEDD8 | ENSOCUP00000049583 | ENSOCUP00000002526 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). | 0.855 |
| BTRC | SKP1 | ENSOCUP00000049583 | ENSOCUP00000020468 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Uncharacterized protein; Belongs to the SKP1 family. | 0.927 |
| BTRC | SKP2 | ENSOCUP00000049583 | ENSOCUP00000007901 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box domain-containing protein. | 0.875 |
| CAND1 | BTRC | ENSOCUP00000004347 | ENSOCUP00000049583 | Cullin associated and neddylation dissociated 1. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.484 |
| CAND1 | COPS5 | ENSOCUP00000004347 | ENSOCUP00000009878 | Cullin associated and neddylation dissociated 1. | COP9 signalosome subunit 5. | 0.484 |
| CAND1 | CUL1 | ENSOCUP00000004347 | ENSOCUP00000002198 | Cullin associated and neddylation dissociated 1. | Cullin 1; Belongs to the cullin family. | 0.996 |
| CAND1 | FBXL3 | ENSOCUP00000004347 | ENSOCUP00000010224 | Cullin associated and neddylation dissociated 1. | F-box and leucine rich repeat protein 3. | 0.530 |
| CAND1 | FBXL5 | ENSOCUP00000004347 | ENSOCUP00000038130 | Cullin associated and neddylation dissociated 1. | F-box and leucine rich repeat protein 5. | 0.433 |
| CAND1 | FBXW11 | ENSOCUP00000004347 | ENSOCUP00000016400 | Cullin associated and neddylation dissociated 1. | F-box and WD repeat domain containing 11. | 0.470 |
| CAND1 | FBXW7 | ENSOCUP00000004347 | ENSOCUP00000007292 | Cullin associated and neddylation dissociated 1. | F-box and WD repeat domain containing 7. | 0.611 |
| CAND1 | NEDD8 | ENSOCUP00000004347 | ENSOCUP00000002526 | Cullin associated and neddylation dissociated 1. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). | 0.914 |
| CAND1 | SKP1 | ENSOCUP00000004347 | ENSOCUP00000020468 | Cullin associated and neddylation dissociated 1. | Uncharacterized protein; Belongs to the SKP1 family. | 0.893 |
| CAND1 | SKP2 | ENSOCUP00000004347 | ENSOCUP00000007901 | Cullin associated and neddylation dissociated 1. | F-box domain-containing protein. | 0.835 |
| COPS5 | CAND1 | ENSOCUP00000009878 | ENSOCUP00000004347 | COP9 signalosome subunit 5. | Cullin associated and neddylation dissociated 1. | 0.484 |
| COPS5 | CUL1 | ENSOCUP00000009878 | ENSOCUP00000002198 | COP9 signalosome subunit 5. | Cullin 1; Belongs to the cullin family. | 0.986 |
