Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HAPLN1Hyaluronan and proteoglycan link protein 1. (354 aa)    
Predicted Functional Partners:
ACAN
Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
 0.961
COL9A1
Collagen type IX alpha 1 chain.
   
 0.673
COL2A1
Fibrillar collagen NC1 domain-containing protein.
   
 0.619
COL11A1
Collagen type XI alpha 1 chain.
   
 0.611
LUM
Lumican.
    
 0.574
MATN3
Matrilin 3.
   
  
 0.572
EDIL3
EGF like repeats and discoidin domains 3.
   
 0.570
TNC
Tenascin C.
   
 0.569
COL9A2
Collagen type IX alpha 2 chain.
   
 0.558
MATN4
Matrilin 4.
   
  
 0.540
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (46%) [HD]