STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTX2Orthodenticle homeobox 2. (289 aa)    
Predicted Functional Partners:
FOXA2
Forkhead box A2.
   
 
 0.857
CRX
Uncharacterized protein.
    
 
 0.855
FGF5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.792
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.766
POU5F1
POU domain protein.
   
 
 0.765
SOX1
SRY-box transcription factor 1.
   
 
 0.765
RCVRN
Recoverin.
   
  
 0.751
HHEX
Homeobox domain-containing protein.
   
  
 0.748
PAX2
Paired box 2.
   
  
 0.747
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
   
  
 0.735
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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