node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MET | MST1R | ENSOCUP00000003111 | ENSOCUP00000008078 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Macrophage stimulating 1 receptor. | 0.715 |
MET | NRP1 | ENSOCUP00000003111 | ENSOCUP00000003952 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Neuropilin; Belongs to the neuropilin family. | 0.523 |
MET | SEMA6A | ENSOCUP00000003111 | ENSOCUP00000035597 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 6A; Belongs to the semaphorin family. | 0.661 |
MET | SEMA6C | ENSOCUP00000003111 | ENSOCUP00000002371 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Sema domain-containing protein; Belongs to the semaphorin family. | 0.660 |
MET | SEMA6D | ENSOCUP00000003111 | ENSOCUP00000006832 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 6D; Belongs to the semaphorin family. | 0.660 |
MST1R | MET | ENSOCUP00000008078 | ENSOCUP00000003111 | Macrophage stimulating 1 receptor. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.715 |
MST1R | NRP1 | ENSOCUP00000008078 | ENSOCUP00000003952 | Macrophage stimulating 1 receptor. | Neuropilin; Belongs to the neuropilin family. | 0.584 |
MST1R | PLXNA1 | ENSOCUP00000008078 | ENSOCUP00000003178 | Macrophage stimulating 1 receptor. | Plexin A1. | 0.483 |
MST1R | PLXNA2 | ENSOCUP00000008078 | ENSOCUP00000003028 | Macrophage stimulating 1 receptor. | Plexin A2. | 0.483 |
MST1R | PLXNA3 | ENSOCUP00000008078 | ENSOCUP00000041487 | Macrophage stimulating 1 receptor. | Sema domain-containing protein. | 0.483 |
MST1R | PLXNA4 | ENSOCUP00000008078 | ENSOCUP00000028707 | Macrophage stimulating 1 receptor. | Plexin A4. | 0.483 |
MST1R | PLXND1 | ENSOCUP00000008078 | ENSOCUP00000011241 | Macrophage stimulating 1 receptor. | Plexin D1. | 0.483 |
MST1R | SEMA6A | ENSOCUP00000008078 | ENSOCUP00000035597 | Macrophage stimulating 1 receptor. | Semaphorin 6A; Belongs to the semaphorin family. | 0.682 |
MST1R | SEMA6C | ENSOCUP00000008078 | ENSOCUP00000002371 | Macrophage stimulating 1 receptor. | Sema domain-containing protein; Belongs to the semaphorin family. | 0.660 |
MST1R | SEMA6D | ENSOCUP00000008078 | ENSOCUP00000006832 | Macrophage stimulating 1 receptor. | Semaphorin 6D; Belongs to the semaphorin family. | 0.660 |
NRP1 | MET | ENSOCUP00000003952 | ENSOCUP00000003111 | Neuropilin; Belongs to the neuropilin family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.523 |
NRP1 | MST1R | ENSOCUP00000003952 | ENSOCUP00000008078 | Neuropilin; Belongs to the neuropilin family. | Macrophage stimulating 1 receptor. | 0.584 |
NRP1 | PLXNA1 | ENSOCUP00000003952 | ENSOCUP00000003178 | Neuropilin; Belongs to the neuropilin family. | Plexin A1. | 0.990 |
NRP1 | PLXNA2 | ENSOCUP00000003952 | ENSOCUP00000003028 | Neuropilin; Belongs to the neuropilin family. | Plexin A2. | 0.999 |
NRP1 | PLXNA3 | ENSOCUP00000003952 | ENSOCUP00000041487 | Neuropilin; Belongs to the neuropilin family. | Sema domain-containing protein. | 0.997 |