FANCD2 protein (Oryctolagus cuniculus) - STRING interaction network

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gene neighborhood

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Score

FANCD2

Uncharacterized protein. (1187 aa)

Predicted Functional Partners:

FANCG

0.999

FANCM

0.999

FANCC

0.999

FANCI

0.999

BRCA2

0.999

FANCL

0.999

FANCF

0.998

UBE2T

0.998

FANCB

0.998

FAN1

0.996

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	FAN1	ENSOCUP00000014514	ENSOCUP00000003722	BRCA2 DNA repair associated.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.514
BRCA2	FANCB	ENSOCUP00000014514	ENSOCUP00000009275	BRCA2 DNA repair associated.	FA complementation group B.	0.742
BRCA2	FANCC	ENSOCUP00000014514	ENSOCUP00000009029	BRCA2 DNA repair associated.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.862
BRCA2	FANCD2	ENSOCUP00000014514	ENSOCUP00000002434	BRCA2 DNA repair associated.	Uncharacterized protein.	0.999
BRCA2	FANCF	ENSOCUP00000014514	ENSOCUP00000007211	BRCA2 DNA repair associated.	FA complementation group F.	0.850
BRCA2	FANCG	ENSOCUP00000014514	ENSOCUP00000005572	BRCA2 DNA repair associated.	FA complementation group G.	0.951
BRCA2	FANCI	ENSOCUP00000014514	ENSOCUP00000009883	BRCA2 DNA repair associated.	FA complementation group I.	0.965
BRCA2	FANCL	ENSOCUP00000014514	ENSOCUP00000049943	BRCA2 DNA repair associated.	FA complementation group L.	0.887
BRCA2	FANCM	ENSOCUP00000014514	ENSOCUP00000006526	BRCA2 DNA repair associated.	FA complementation group M.	0.933
BRCA2	UBE2T	ENSOCUP00000014514	ENSOCUP00000008838	BRCA2 DNA repair associated.	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.	0.601
FAN1	BRCA2	ENSOCUP00000003722	ENSOCUP00000014514	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	BRCA2 DNA repair associated.	0.514
FAN1	FANCB	ENSOCUP00000003722	ENSOCUP00000009275	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group B.	0.668
FAN1	FANCC	ENSOCUP00000003722	ENSOCUP00000009029	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.499
FAN1	FANCD2	ENSOCUP00000003722	ENSOCUP00000002434	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Uncharacterized protein.	0.996
FAN1	FANCF	ENSOCUP00000003722	ENSOCUP00000007211	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group F.	0.547
FAN1	FANCG	ENSOCUP00000003722	ENSOCUP00000005572	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group G.	0.567
FAN1	FANCI	ENSOCUP00000003722	ENSOCUP00000009883	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group I.	0.918
FAN1	FANCL	ENSOCUP00000003722	ENSOCUP00000049943	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group L.	0.723
FAN1	FANCM	ENSOCUP00000003722	ENSOCUP00000006526	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group M.	0.985
FAN1	UBE2T	ENSOCUP00000003722	ENSOCUP00000008838	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.	0.527