| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRCA2 | FAN1 | ENSOCUP00000014514 | ENSOCUP00000003722 | BRCA2 DNA repair associated. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.418 |
| BRCA2 | FANCA | ENSOCUP00000014514 | ENSOCUP00000015531 | BRCA2 DNA repair associated. | FA complementation group A. | 0.883 |
| BRCA2 | FANCC | ENSOCUP00000014514 | ENSOCUP00000009029 | BRCA2 DNA repair associated. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.819 |
| BRCA2 | FANCD2 | ENSOCUP00000014514 | ENSOCUP00000002434 | BRCA2 DNA repair associated. | Uncharacterized protein. | 0.998 |
| BRCA2 | FANCE | ENSOCUP00000014514 | ENSOCUP00000029800 | BRCA2 DNA repair associated. | FA complementation group E. | 0.769 |
| BRCA2 | FANCF | ENSOCUP00000014514 | ENSOCUP00000007211 | BRCA2 DNA repair associated. | FA complementation group F. | 0.801 |
| BRCA2 | FANCG | ENSOCUP00000014514 | ENSOCUP00000005572 | BRCA2 DNA repair associated. | FA complementation group G. | 0.952 |
| BRCA2 | FANCI | ENSOCUP00000014514 | ENSOCUP00000009883 | BRCA2 DNA repair associated. | FA complementation group I. | 0.965 |
| BRCA2 | FANCL | ENSOCUP00000014514 | ENSOCUP00000049943 | BRCA2 DNA repair associated. | FA complementation group L. | 0.836 |
| BRCA2 | FANCM | ENSOCUP00000014514 | ENSOCUP00000006526 | BRCA2 DNA repair associated. | FA complementation group M. | 0.870 |
| FAN1 | BRCA2 | ENSOCUP00000003722 | ENSOCUP00000014514 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | BRCA2 DNA repair associated. | 0.418 |
| FAN1 | FANCA | ENSOCUP00000003722 | ENSOCUP00000015531 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group A. | 0.783 |
| FAN1 | FANCC | ENSOCUP00000003722 | ENSOCUP00000009029 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.732 |
| FAN1 | FANCD2 | ENSOCUP00000003722 | ENSOCUP00000002434 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Uncharacterized protein. | 0.996 |
| FAN1 | FANCE | ENSOCUP00000003722 | ENSOCUP00000029800 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group E. | 0.614 |
| FAN1 | FANCF | ENSOCUP00000003722 | ENSOCUP00000007211 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group F. | 0.707 |
| FAN1 | FANCG | ENSOCUP00000003722 | ENSOCUP00000005572 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group G. | 0.741 |
| FAN1 | FANCI | ENSOCUP00000003722 | ENSOCUP00000009883 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group I. | 0.941 |
| FAN1 | FANCL | ENSOCUP00000003722 | ENSOCUP00000049943 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group L. | 0.746 |
| FAN1 | FANCM | ENSOCUP00000003722 | ENSOCUP00000006526 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group M. | 0.873 |