STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCN2Cellular communication network factor 2. (437 aa)    
Predicted Functional Partners:
COL1A1
Collagen alpha-1(I) chain.
   
  
 0.863
LOC103345451
TGFb_propeptide domain-containing protein.
   
  
 0.858
ENSOCUP00000037329
TGFb_propeptide domain-containing protein.
   
  
 0.858
ENSOCUP00000044284
TGFb_propeptide domain-containing protein.
   
  
 0.858
G1TC56_RABIT
TGFb_propeptide domain-containing protein.
   
  
 0.841
SMAD2
Mothers against decapentaplegic homolog.
   
  
 0.828
SMAD3
SMAD family member 3.
   
  
 0.824
MMP9
Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).
   
 
 0.823
ANKRD1
Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes (By similarity).
   
 
 0.816
LATS1
Large tumor suppressor kinase 1.
      
 0.816
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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