Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNS4Tensin 4. (722 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.958
G1TNP0_RABIT
Uncharacterized protein.
 
 
  
 0.913
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.659
ITGB2
Integrin beta.
   
 0.659
TLN1
Talin 1.
   
 
 0.638
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
 
 
  
 0.624
TLN2
Talin 2.
   
 
 0.612
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.606
CBL
Cbl proto-oncogene.
    
 
 0.575
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.555
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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