STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)    
Predicted Functional Partners:
MDH2
Malate dehydrogenase 2.
   
 
 0.970
MDH1
Malate dehydrogenase.
   
 
 0.963
ENO3
Beta-enolase.
     
 0.962
ENO2
Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.
   
 
 0.961
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.958
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 
 0.953
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.953
ENO4
Enolase 4.
   
 
 0.949
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.925
PCK1
Phosphoenolpyruvate carboxykinase 1.
  
0.908
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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