SETD2 protein (Oryctolagus cuniculus) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SETD2

Uncharacterized protein. (625 aa)

Predicted Functional Partners:

H3C13

0.923

POLR2C

0.911

IWS1

0.905

PBRM1

0.899

POLR2B

0.886

H3-3A

0.879

KDM6A

0.873

LOC100345683

0.868

LOC100357927

0.867

LOC100344410

0.867

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3-3A	H3C13	ENSOCUP00000018693	ENSOCUP00000016501	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Histone H3; Belongs to the histone H3 family.	0.913
H3-3A	IWS1	ENSOCUP00000018693	ENSOCUP00000004196	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Interacts with SUPT6H, CTD assembly factor 1.	0.532
H3-3A	KDM6A	ENSOCUP00000018693	ENSOCUP00000034429	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Lysine demethylase 6A.	0.911
H3-3A	LOC100344410	ENSOCUP00000018693	ENSOCUP00000019185	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Histone domain-containing protein.	0.863
H3-3A	LOC100345683	ENSOCUP00000018693	ENSOCUP00000017475	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Histone H3; Belongs to the histone H3 family.	0.863
H3-3A	PBRM1	ENSOCUP00000018693	ENSOCUP00000008471	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Polybromo 1.	0.788
H3-3A	POLR2B	ENSOCUP00000018693	ENSOCUP00000014066	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.659
H3-3A	POLR2C	ENSOCUP00000018693	ENSOCUP00000012875	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	RNA polymerase II subunit C.	0.588
H3-3A	SETD2	ENSOCUP00000018693	ENSOCUP00000002465	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	Uncharacterized protein.	0.879
H3C13	H3-3A	ENSOCUP00000016501	ENSOCUP00000018693	Histone H3; Belongs to the histone H3 family.	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	0.913
H3C13	IWS1	ENSOCUP00000016501	ENSOCUP00000004196	Histone H3; Belongs to the histone H3 family.	Interacts with SUPT6H, CTD assembly factor 1.	0.533
H3C13	KDM6A	ENSOCUP00000016501	ENSOCUP00000034429	Histone H3; Belongs to the histone H3 family.	Lysine demethylase 6A.	0.905
H3C13	LOC100344410	ENSOCUP00000016501	ENSOCUP00000019185	Histone H3; Belongs to the histone H3 family.	Histone domain-containing protein.	0.936
H3C13	LOC100345683	ENSOCUP00000016501	ENSOCUP00000017475	Histone H3; Belongs to the histone H3 family.	Histone H3; Belongs to the histone H3 family.	0.936
H3C13	LOC100357927	ENSOCUP00000016501	ENSOCUP00000012002	Histone H3; Belongs to the histone H3 family.	Histone domain-containing protein.	0.586
H3C13	PBRM1	ENSOCUP00000016501	ENSOCUP00000008471	Histone H3; Belongs to the histone H3 family.	Polybromo 1.	0.851
H3C13	POLR2B	ENSOCUP00000016501	ENSOCUP00000014066	Histone H3; Belongs to the histone H3 family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.657
H3C13	POLR2C	ENSOCUP00000016501	ENSOCUP00000012875	Histone H3; Belongs to the histone H3 family.	RNA polymerase II subunit C.	0.588
H3C13	SETD2	ENSOCUP00000016501	ENSOCUP00000002465	Histone H3; Belongs to the histone H3 family.	Uncharacterized protein.	0.923
IWS1	H3-3A	ENSOCUP00000004196	ENSOCUP00000018693	Interacts with SUPT6H, CTD assembly factor 1.	Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]	0.532