STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB14Growth factor receptor bound protein 14. (540 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.931
FGFR1
Fibroblast growth factor receptor.
    
 0.794
IGF1R
Tyrosine-protein kinase receptor.
    
 0.688
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.622
FRS2
Fibroblast growth factor receptor substrate 2.
    
 0.602
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.601
GRB2
Growth factor receptor bound protein 2.
    
0.599
CRKL
CRK like proto-oncogene, adaptor protein.
    
0.594
NRAS
NRAS proto-oncogene, GTPase.
    
 0.594
CPXCR1
Uncharacterized protein.
      
 0.569
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.