node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD44 | EGFR | ENSOCUP00000048202 | ENSOCUP00000009041 | CD44 molecule (Indian blood group). | Receptor protein-tyrosine kinase. | 0.973 |
CD44 | ENSOCUP00000040886 | ENSOCUP00000048202 | ENSOCUP00000040886 | CD44 molecule (Indian blood group). | Uncharacterized protein. | 0.527 |
CD44 | FN1 | ENSOCUP00000048202 | ENSOCUP00000008718 | CD44 molecule (Indian blood group). | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.963 |
CD44 | LAMP1 | ENSOCUP00000048202 | ENSOCUP00000019802 | CD44 molecule (Indian blood group). | Lysosomal associated membrane protein 1. | 0.440 |
CD44 | LGALS3 | ENSOCUP00000048202 | ENSOCUP00000044843 | CD44 molecule (Indian blood group). | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.811 |
CD44 | TLR4 | ENSOCUP00000048202 | ENSOCUP00000001909 | CD44 molecule (Indian blood group). | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.922 |
CLEC7A | LGALS3 | ENSOCUP00000014442 | ENSOCUP00000044843 | C-type lectin domain containing 7A. | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.844 |
CLEC7A | TLR4 | ENSOCUP00000014442 | ENSOCUP00000001909 | C-type lectin domain containing 7A. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.573 |
EGFR | CD44 | ENSOCUP00000009041 | ENSOCUP00000048202 | Receptor protein-tyrosine kinase. | CD44 molecule (Indian blood group). | 0.973 |
EGFR | FN1 | ENSOCUP00000009041 | ENSOCUP00000008718 | Receptor protein-tyrosine kinase. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.757 |
EGFR | LAMP1 | ENSOCUP00000009041 | ENSOCUP00000019802 | Receptor protein-tyrosine kinase. | Lysosomal associated membrane protein 1. | 0.631 |
EGFR | LGALS3 | ENSOCUP00000009041 | ENSOCUP00000044843 | Receptor protein-tyrosine kinase. | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.825 |
EGFR | TLR4 | ENSOCUP00000009041 | ENSOCUP00000001909 | Receptor protein-tyrosine kinase. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.606 |
ENSOCUP00000040886 | CD44 | ENSOCUP00000040886 | ENSOCUP00000048202 | Uncharacterized protein. | CD44 molecule (Indian blood group). | 0.527 |
ENSOCUP00000040886 | FN1 | ENSOCUP00000040886 | ENSOCUP00000008718 | Uncharacterized protein. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.997 |
ENSOCUP00000040886 | LGALS3 | ENSOCUP00000040886 | ENSOCUP00000044843 | Uncharacterized protein. | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.827 |
FN1 | CD44 | ENSOCUP00000008718 | ENSOCUP00000048202 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | CD44 molecule (Indian blood group). | 0.963 |
FN1 | EGFR | ENSOCUP00000008718 | ENSOCUP00000009041 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | Receptor protein-tyrosine kinase. | 0.757 |
FN1 | ENSOCUP00000040886 | ENSOCUP00000008718 | ENSOCUP00000040886 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | Uncharacterized protein. | 0.997 |
FN1 | LGALS3 | ENSOCUP00000008718 | ENSOCUP00000044843 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.798 |