Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC34A2Solute carrier family 34 member 2. (715 aa)    
Predicted Functional Partners:
SLC9A3R1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...]
    
 0.914
SLC34A1
Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.
   
 
  0.863
ROS1
Tyrosine-protein kinase receptor.
   
 0.772
SLC17A1
Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
   
  
 0.771
LRIG3
Leucine rich repeats and immunoglobulin like domains 3.
    
 
 0.759
SFTPC
Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
   
  
 0.728
SFTPB
Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
   
 
 0.727
DHX33
DEAH-box helicase 33.
   
  0.723
SFTPD
Surfactant protein D.
   
 0.710
CCDC6
Coiled-coil domain containing 6.
      
 0.703
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.