STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G1SIX8_RABITCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (400 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.975
CDC20B
Cell division cycle 20B.
   
 0.958
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.950
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.945
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.943
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.939
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.935
CKS1B
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.924
CDKN1A
Uncharacterized protein.
    
 0.893
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.882
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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