| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABAT | ACLY | ENSOCUP00000047043 | ENSOCUP00000029663 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.408 |
| ABAT | ALDH18A1 | ENSOCUP00000047043 | ENSOCUP00000005157 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.531 |
| ABAT | ALDH5A1 | ENSOCUP00000047043 | ENSOCUP00000002664 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.947 |
| ABAT | GLUD1 | ENSOCUP00000047043 | ENSOCUP00000039862 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.851 |
| ACLY | ABAT | ENSOCUP00000029663 | ENSOCUP00000047043 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.408 |
| ACLY | ALDH18A1 | ENSOCUP00000029663 | ENSOCUP00000005157 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.664 |
| ACLY | ALDH5A1 | ENSOCUP00000029663 | ENSOCUP00000002664 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.888 |
| ACLY | CS | ENSOCUP00000029663 | ENSOCUP00000049078 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase; Belongs to the citrate synthase family. | 0.998 |
| ACLY | GLUD1 | ENSOCUP00000029663 | ENSOCUP00000039862 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.899 |
| ACLY | IDH2 | ENSOCUP00000029663 | ENSOCUP00000048165 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.895 |
| ACLY | IDH3A | ENSOCUP00000029663 | ENSOCUP00000044748 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.658 |
| ACLY | MDH1 | ENSOCUP00000029663 | ENSOCUP00000005340 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.971 |
| ACLY | MDH2 | ENSOCUP00000029663 | ENSOCUP00000035179 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase 2. | 0.981 |
| ACLY | OGDH | ENSOCUP00000029663 | ENSOCUP00000002096 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Oxoglutarate dehydrogenase. | 0.920 |
| ALDH18A1 | ABAT | ENSOCUP00000005157 | ENSOCUP00000047043 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.531 |
| ALDH18A1 | ACLY | ENSOCUP00000005157 | ENSOCUP00000029663 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.664 |
| ALDH18A1 | ALDH5A1 | ENSOCUP00000005157 | ENSOCUP00000002664 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.872 |
| ALDH18A1 | CS | ENSOCUP00000005157 | ENSOCUP00000049078 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.822 |
| ALDH18A1 | GLUD1 | ENSOCUP00000005157 | ENSOCUP00000039862 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.990 |
| ALDH18A1 | IDH2 | ENSOCUP00000005157 | ENSOCUP00000048165 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.715 |